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    发布者:材料与能源学院  发布时间:2021-07-15  浏览次数:1791



    一、个人信息:                            

    姓名:  李兆栋; 

    出生日期: 1986/01/06;

    籍贯:  山东省临沂市平邑县

                                                            

    二、亚博平台下载的联系方式:

    e-mail: ;

    个人简述(300字内)
    李兆栋,博士,教授,博士生导师,2020年入选国家海外高层次人才引进计划(青年项目)。主持国家自然科学基金1项,省、厅级项目3余项。在化学顶级期刊jacs, angew, nat. commun.等发表学术论文30余篇。

    、教育背景(依次介绍博士、硕士、本科)

    2017.10 – 2018.09: 瑞士洛桑联邦理工大学应用化学研究所博士后,导师:prof. jieping zhu

    2014.09 – 2017.09: 瑞士苏黎世大学化学系博士后,导师:prof. cristina nevado

    2009.09 – 2014.07: 中国科学院上海有机化学研究所,硕博连读,获理学博士学位;

    导师:李超忠研究员;

    2005.09 – 2009.07:西南大学化学化工学院化学系,本科,获理学学士学位;

     

    、工作经历(主要工作简历 主要学术兼职)
    201810月至今,华南农业大学材料与能源学院。

    六、科研方向
    1)导向合成的自由基反应方法学研究。将自由基独特反应性与过渡金属催化相结合,发展环境友好的有机合成新反应。

    2)自由基反应在天然产物全合成中的应用。应用自由基偶联、环合、脱羧官能团化等反应,实现结构复杂天然产物特别是生物碱类分子合成中的关键化学转化和骨架构筑。

    3)关键药物中间体及新型农药的创制。运用新方法及设计新路线,开发具有竞争力的药物中间体新路线;在此基础上,开发新农药。

    七、代表性科研论著

    发表论文

    1. remote c(sp3)-h functionalization enabled by copper-catalyzed cross coupling of oxime esters with terminal alkynes: synthesis of γ-alkynyl nitriles and ketones. 

    zhaodong li, rubén o. torres-ochoa, qian wang, jieping zhu*; nat. commun. 2020, 11, 403.

    2. copper-catalyzed arylation of remote c(sp3)-h bonds in carboxamides and sulfonamides. 

    zhaodong li, qian wang, jieping zhu*; angew. chem. int. ed. 2018, 57, 13288.

    3. ni-catalyzed stereoselective bis-carbofunctionalization of alkyne.

    zhaodong li, andrés garcía-domínguez, cristina nevado*; angew. chem. int. ed. 2016, 55, 6938.

    4. pd-catalyzed stereoselective carboperfluoroalkylation of alkynes.

    zhaodong li, andrés garcía-domínguez, and cristina nevado*; j. am. chem. soc. 2015, 137, 11610.

    5. silver-catalyzed radical fluorination of alkylboronates in aqueous solution

    zhaodong li, zhentao wang, lin zhu, xinqiang tan, and chaozhong li*; j. am.

    chem. soc. 2014, 136, 16439.

    6. silver-catalyzed  radical  aminofluorination  of  unactivated  alkenes  in aqueous media.

    zhaodong  li,  liyan  song,  chaozhong  li*; j. am. chem. soc. 2013, 135,  4640.

    7. transition-metal-free, room temperature radical azidofluorination of unactivated alkenes in aqueous media.

    zhaodong  li, chengwei zhang,  lin  zhu, chao  liu, chaozhong  li*; org. chem. front. 2014,  1, 100.

    8. stereoselective carboperfluoroalkylation of internl alkynes: mechanistic insights.

    zhaodong  li, estíbaliz  merino, cristina  nevado*; topics  in  catalysis, 2017, 60,  545.

    9. coppercatalyzed cross coupling of benzylic bromides with arylboronic acids: synthesis of diarylalkanes and preliminary antifungal evaluation against magnaporthe grisea.

    zhu zhu, jinggong liu, shoucheng dong, bolai chen*, zhenghui wang*, ri‐yuan tang*, zhaodong li*, asian j. org. chem. 2020, 9, 631.

    10. photo‐mediated decarboxylative cross coupling of quinoxalin‐2(1h)‐ones with aliphatic carboxylic acids in aqueous solution: synthesis of alkylated quinoxalin‐2(1h)‐ones and preliminary antifungal evaluation against magnaporthe grisea.

    , , , *, *, asian j. org. chem. 2020, 9, 782 .

    11. transtion-metal-free, intermolecular azidoheteroarylation of alkenes: efficient access to β-azidoalkylated quinoxalinones and preliminary antifungal evaluation against magnaporthe grisea. 

    yiming du, yihan chen, yun-lin. liu, weiwei qin*, zhaodong  li*, synthesis 2020, 52, 2395.

    12. transition metal-free, three-component trifluoromethylative heteroarylation of unactivated alkenes: efficient access to β-trifluoromethylated quinoxalinones and preliminary antifungal evaluation against magnaporthe grisea.

    zhuoxian shao, shaoyi zhang, yihan chen, yunlin liu, ri-yuan tang,* zhaodong li*, tetrahedron, 2020, 76, 131199.

    13. fluoroalkylation of allylic alcohols with concomitant aryl migration: efficient access to fluoroalkylated ketones and preliminary antifungal evaluation against magnaporthe grisea.

    yanhu zhang, ziyang ren , yunlin liu, zhentao wang,* zhaodong li*, eur. j. org. chem. 2020, 5192.

    14. nickel-catalyzed  reductive  dicarbofunctionalization  of  alkene.

    andrés  garcía domínguez, zhaodong  li,  and  cristina  nevado*; j. am. chem. soc. 2017, 139, 6835.

    15. γ-functionalizations of amines  through  visible-light-mediated,  redox-neutral c−c  bond  cleavage.  

    wei  shu, alexandre  genoux, zhaodong  li,  and  cristina nevado*; angew. chem. int. ed. 2017, 56, 10521.

    16. silver-catalyzed decarboxylative radical azidation of aliphatic carboxylic acids in aqueous solution.

    chao liu, xiaoqing wang, zhaodong  li, lei cui, chaozhong li*. j. am. chem.

    soc. 2015, 137, 9820.

    17. silver-catalyzed radical phosphonofluorination of unactivated alkenes in aqueous solution.

    chengwei  zhang, zhaodong  li,  chaozhong  li*; j. am. chem. soc. 2013, 135, 14082.

    18. silver-catalyzed  decarboxylative  fluorination of aliphatic carboxylic acids in  aqueous solution.

    feng yin, zhentao wang, zhaodong li, chaozhong li*; j. am. chem. soc. 2012, 134, 10401.

    19. silver-catalyzed decarboxylative chlorination of aliphatic carboxylic acids.

    zhentao wang, zhu lin, feng yin, zhongquan su, zhaodong li, chaozhong li*;

    j. am. chem. soc. 2012, 134, 4258.

     

    八、 科研项目

    主持基金

    1. 国家自然科学基金青年基金:《可见光介导过渡金属催化的烷基自由基的多氟芳基化反应研究》; 

    2. 广东省自然科学基金面上项目:《多氟芳烃导向农药分子设计与输导机制研究》

    3. 广东省自然科学基金面上项目:《氮杂环丁烷衍生物自由基开环偶联反应研究及其在合成新型农药分子中的应用》

     

    九、 获奖情况
    20166月,上海市优秀博士论文

    20151月, novartis post-doctoral fellowship


     


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